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Nicely done, Awais! The points you make dovetail very neatly with the piece I did for Psychiatric Times, in which I discuss the nature of the placebo condition; what the "15%" figure in the Stone et al study really means for clinicians; and why a narrow fixation on numbers can obscure the main reason psychiatric medications are worthwhile; i.e., because they reduce, even if modestly, the suffering and incapacity of extremely debilitating and sometimes lethal illnesses.

https://www.psychiatrictimes.com/view/antidepressants-placebos-and-lithium-some-parting-thoughts

All the best,

Ron

Ronald W. Pies, MD

Professor Emeritus of Psychiatry

SUNY Upstate Medical University

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